Lower?level associations in Gilles de la Tourette syndrome: Convergence between hyperbinding of stimulus and response features and procedural hyperfunctioning theories
نویسندگان
چکیده
Gilles de la Tourette syndrome (GTS) can be characterized by enhanced cognitive functions related to creating, modifying and maintaining connections between stimuli responses (S-R links). Specifically, two areas, procedural sequence learning and, as a novel finding, also event file binding, show converging evidence of hyperfunctioning in GTS. In this review, we describe how these considered mechanisms behind habitual behaviour, such tics Moreover, the presence both binding same disorder treated for their functional connections, even beyond Importantly though, argue that are not interchangeable: they have different time scales, sensitivities potential impairment action sequencing distinguishable contributions profile An integrated theoretical account hyperbinding hyperlearning GTS allows formulate predictions emergence, activation long-term persistence
منابع مشابه
[Gilles de la tourette syndrome: clinical spectrum and management].
OBJECTIVE To present the current concepts of the clinical phenomenology and natural history of Gilles de la Tourette syndrome (GTS), differential diagnosis with other involuntary movements, its pathogenesis and current management. DEVELOPMENT GTS is a disorder characterized by a spectrum of both motor and sonic tics, and a spectrum of behavioral disorders. There is not a biological marker tha...
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Investigators from Centre de Reference National Maladie Rare 'Syndrome Gilles de la Tourette' and Sorbonne University report white matter abnormalities in the pathways connecting the cerebral cortex, basal ganglia, and thalamus in a group of 49 adults with Tourette syndrome (TS).
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UNLABELLED Although there only have been a limited number of double-blind, placebo controlled trials, antipsychotics are considered to be effective drugs for the treatment of tics in Gilles de la Tourette syndrome (GTS). Evidence concerning the efficacy of olanzapine and other atypical antipsychotics in the treatment of tics in GTS is growing, but still limited. Little is known about the use of...
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Saccadic eye movements, fixation and smooth pursuit were studied in 28 children with Gilles de la Tourette syndrome and found to be normal. A link has been postulated between Gilles de la Tourette syndrome and other movement disorders. The results obtained in the present series do not support this hypothesis.
متن کاملMotor-Cortical Interaction in Gilles de la Tourette Syndrome
BACKGROUND In Gilles de la Tourette syndrome (GTS) increased activation of the primary motor cortex (M1) before and during movement execution followed by increased inhibition after movement termination was reported. The present study aimed at investigating, whether this activation pattern is due to altered functional interaction between motor cortical areas. METHODOLOGY/PRINCIPAL FINDINGS 10 ...
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ژورنال
عنوان ژورنال: European Journal of Neuroscience
سال: 2021
ISSN: ['0953-816X', '1460-9568']
DOI: https://doi.org/10.1111/ejn.15366